Installation: https://tech.knime.org/installation-0 c. Update extensions: https://www.knime.org/downloads/update 2) Importing workflows - Download workflows from http://bioinformatics.iyte.edu.tr/supplements/izmir - Open KNIME - On the left side of KNIME window, there is a box with LOCAL \(Local Workspace) \(Figure 1), right click to that area

“select import KNIME workflow” \(https://tech.knime.org/workbench) -
{"action": "select", "output": "", "reagent": ["import KNIME workflow"]}
If you want to make modifications to the workflow you can click on the nodes .

If you want to add another study with different feature set copy paste one of the meta-nodes \(e.g. #####%%%%% output "another study" are used in line12
{"action": "do", "output": "another study", "container": ["the meta-nodes"]}
Ng) connect it in the same way as the existing ones.
{"action": "connect", "output": "", "device": [""]}
Right click to change meta-node name.
{"action": "embed", "output": "", "reagent": ["another study"]}
select Reconfigure

Then go into your meta-node select filter \(feature selection).
{"action": "go", "output": "", "reagent": ["", "", ""]}
Inside that meta-node, there are two column filter nodes; one for learning another for testing data, #####%%%%% output "another" are not used
{"action": "have", "output": "another", "container": ["that meta-node"], "reagent": [""]}
in these nodes select your choice of features.

If your data has no such columns you can use RowID node to create unique accession values. #####%%%%% output "unique accession values" are not used
{"action": "have", "output": "unique accession values", "container": ["RowID node"], "reagent": [""]}