Part of Advances in Neural Information Processing Systems 13 (NIPS 2000)

*Ulrik Kjems, Lars Hansen, Stephen Strother*

We demonstrate that statistical analysis of ill-posed data sets is subject to a bias, which can be observed when projecting indepen(cid:173) dent test set examples onto a basis defined by the training exam(cid:173) ples. Because the training examples in an ill-posed data set do not fully span the signal space the observed training set variances in each basis vector will be too high compared to the average vari(cid:173) ance of the test set projections onto the same basis vectors. On basis of this understanding we introduce the Generalizable Singu(cid:173) lar Value Decomposition (GenSVD) as a means to reduce this bias by re-estimation of the singular values obtained in a conventional Singular Value Decomposition, allowing for a generalization perfor(cid:173) mance increase of a subsequent statistical model. We demonstrate that the algorithm succesfully corrects bias in a data set from a functional PET activation study of the human brain.

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Ill-posed Data Sets

An ill-posed data set has more dimensions in each example than there are examples. Such data sets occur in many fields of research typically in connection with image measurements. The associated statistical problem is that of extracting structure from the observed high-dimensional vectors in the presence of noise. The statistical analysis can be done either supervised (Le. modelling with target values: classifi(cid:173) cation, regresssion) or unsupervised (modelling with no target values: clustering, PCA, ICA). In both types of analysis the ill-posedness may lead to immediate prob(cid:173) lems if one tries to apply conventional statistical methods of analysis, for example the empirical covariance matrix is prohibitively large and will be rank-deficient.

A common approach is to use Singular Value Decomposition (SVD) or the analogue Principal Component Analysis (PCA) to reduce the dimensionality of the data. Let the N observed i-dimensional samples Xj, j = L .N, collected in the data matrix X = [Xl ... XN] of size I x N, I> N . The SVD-theorem states that such a matrix can be decomposed as

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